Individualized home-based exercise and nutrition interventions improve frailty in older adults: a randomized controlled trial

Autor:	Yaw-Wen Kang, Likwang Chen, Tsung-Jen Hsieh, Shao Yuan Chuang, Szu-Yun Wu, Hsing-Yi Chang, Li-Lin Hsu, Chih-Cheng Hsu, Shin-Chang Su, Wen-Harn Pan, Chun-Wei Chen, Ming-Hsia Hu
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	medicine.medical_specialty Individualized home-based interventions Frail Older Adults Medicine (miscellaneous) Physical Therapy Sports Therapy and Rehabilitation Clinical nutrition law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law medicine 030212 general & internal medicine Home based exercise Adverse effect Exercise lcsh:RC620-627 Nutrition Nutrition and Dietetics Nutrition Interventions Frailty business.industry lcsh:Public aspects of medicine lcsh:RA1-1270 Mental health Confidence interval lcsh:Nutritional diseases. Deficiency diseases Older adults Physical therapy business 030217 neurology & neurosurgery
Zdroj:	International Journal of Behavioral Nutrition and Physical Activity, Vol 16, Iss 1, Pp 1-15 (2019)
ISSN:	1479-5868
Popis:	Background Frail older adults are predisposed to multiple comorbidities and adverse events. Recent interventional studies have shown that frailty can be improved and managed. In this study, effective individualized home-based exercise and nutrition interventions were developed for reducing frailty in older adults. Methods This study was a four-arm, single-blind, randomized controlled trial conducted between October 2015 and June 2017 at Miaoli General Hospital in Taiwan. Overall, 319 pre-frail or frail older adults were randomly assigned into one of the four study groups (control, exercise, nutrition, and exercise plus nutrition [combination]) and followed up during a 3-month intervention period and 3-month self-maintenance period. Improvement in frailty scores was the primary outcome. Secondary outcomes included improvements in physical performance and mental health. The measurements were performed at baseline, 1 month, 3 months, and 6 months. Results At the 6-month measurement, the exercise (difference in frailty score change from baseline: − 0.23; 95% confidence interval [CI]: − 0.41, − 0.05; p = 0.012), nutrition (− 0.28; 95% CI: − 0.46, − 0.11; p = 0.002), and combination (− 0.34; 95% CI: − 0.52, − 0.16; p Conclusions The designated home-based exercise and nutrition interventions can help pre-frail or frail older adults to improve their frailty score and physical performance. Trial registration Retrospectively registered at ClinicalTrials.gov (identifier: NCT03477097); registration date: March 26, 2018.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099dade8b90037f9553396b01c807245 https://doaj.org/article/90bcf5f1067d4d61b3ee68f9ca30199b Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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