Structural changes in dermal collagen and oxidative stress levels in the skin of Japanese overweight males
| Autor: | Misako Dai, Kazuhiro Ogai, Gojiro Nakagami, T. Nishizawa, Takeo Minematsu, Toshio Nakatani, Ai Ibuki, Mayumi Okuwa, Junko Sugama, Aya Sato, Motoko Horii, Y. Fujimoto, Masaru Matsumoto, Hiromi Sanada |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Protein Conformation Pharmaceutical Science Adipose tissue Dermatology Overweight medicine.disease_cause Muscle hypertrophy Colloid and Surface Chemistry Dermis Internal medicine Drug Discovery Humans Medicine Skin business.industry Echogenicity Anatomy Middle Aged Oxidative Stress Cross-Sectional Studies medicine.anatomical_structure Endocrinology Chemistry (miscellaneous) Case-Control Studies Abdomen Collagen medicine.symptom business Body mass index Oxidative stress |
| Zdroj: | International Journal of Cosmetic Science. 36:477-484 |
| ISSN: | 0142-5463 |
| DOI: | 10.1111/ics.12145 |
| Popis: | SynopsisObjective It has been reported that obese people have poorly organized dermal collagen structure because of the degradation of collagen fibers, which is caused by an increase in oxidative stress levels associated with the hypertrophy of subcutaneous adipose cells. However, it is unclear whether an increase in oxidative stress levels caused by the accumulation of subcutaneous adipose tissue and a change in the dermal structure also occur in overweight and obese Japanese people. The objectives of this study are to identify structural changes that occur in the dermis and to measure the levels of oxidative stress in Japanese overweight males. Methods The overweight group included 43 Japanese male volunteers aged between 25 and 64 years and with a body mass index (BMI) of ≥25 and |
| Databáze: | OpenAIRE |
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