Myoepithelioma of the Nasal Septum: A Rare Case of Extrasalivary Gland Involvement
Autor: | Thiago Cavalcante Ribeiro, Eriko Vinhaes, Nilvano Alves de Andrade, Amanda Canário Andrade Azevedo, Tatiane Costa Camurugy, Gustavo Barreto da Cunha, Nara Nunes Barbosa Costa |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Nasal cavity
Pathology medicine.medical_specialty Myoepithelioma Nostril Calponin Case Report macromolecular substances Benign tumor 03 medical and health sciences Cytokeratin 0302 clinical medicine Biopsy Nasal septum otorhinolaryngologic diseases Medicine 030223 otorhinolaryngology biology medicine.diagnostic_test business.industry General Medicine medicine.disease lcsh:Otorhinolaryngology lcsh:RF1-547 medicine.anatomical_structure 030220 oncology & carcinogenesis biology.protein business |
Zdroj: | Case Reports in Otolaryngology, Vol 2017 (2017) Case Reports in Otolaryngology |
ISSN: | 2090-6773 2090-6765 |
Popis: | Introduction. The myoepithelioma is a rare benign tumor, most frequently found in the salivary glands. The extrasalivary gland involvement is even rarer and few cases involving the nasal cavity have been reported in the literature. Case Report. MES, a 54-year-old woman, complaining of progressive nasal obstruction and mild epistaxis through the right nostril which had developed 1 year previously. Computed tomography scan showed tumor with heterogeneous contrast enhancement occupying the right nasal cavity, moving contralaterally in the nasal septum. Excisional biopsy was performed through endoscopic surgery of the mass that was inserted at the nasal septum. Pathological and immunohistochemical exams concluded myoepithelioma. Discussion. The main symptoms of nasal myoepitheliomas are nasal obstruction and epistaxis. Immunohistochemistry is necessary to confirm the diagnosis, typically positive for cytokeratin and S-100, calponin, smooth muscle actin, myosin, vimentin, glial fibrillary acidic protein (GFAP), and carcinoembryonic antigen. The main marker for myoepithelioma is the S-100 protein. In our case, it was positive for cytokeratin, S-100, calponin, actin smooth muscle, and GFAP. In all cases reported in the literature surgical treatment was performed and the recurrence was associated with incomplete tumor resection. Final Comments. The myoepithelioma is a rare differential diagnosis of nasal tumors and its treatment is the total lesion excision. |
Databáze: | OpenAIRE |
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