Risk Factors for Development of Endophthalmitis after Open Globe Injury in Children: A Case-Control Study

Autor:	Rashmi Ingale, Amit Mohan, Chintan Shah, Pratik Shenoy, Alok Sen, Gaurav Mohan Kohli, Amrita Tiwari, Pradhnya Sen
Rok vydání:	2021
Předmět:	Ophthalmology medicine.medical_specialty Endophthalmitis business.industry Emergency medicine Open Globe Injury Case-control study Immunology and Allergy Medicine business medicine.disease
Zdroj:	Ocular Immunology and Inflammation. 30:1633-1638
ISSN:	1744-5078 0927-3948
DOI:	10.1080/09273948.2021.1928237
Popis:	To identify risk-factors for developing endophthalmitis following open globe injury (OGI) in children.Retrospective, single-center, case-control study of children aged18 years who sustained OGI.Our cohort of 93 eyes consisted of 30 cases (Group A- endophthalmitis) and 63 controls (Group B- no endophthalmitis). Twenty-four eyes (80%) diagnosed with endophthalmitis presented after 24 hours of injury. The presence of central corneal zone-1 injuries (Odd ratio [OR]: 6.64, p= 0.001) and vitreous in wound (OR: 3.53) were associated with the risk of developing endophthalmitis. (p=0.05) Additionally the presence of iris prolapse (OR: 4.76) and posterior capsular rupture (PCR) (OR: 5.80) increased the risk of developing endophthalmitis.(p0.05) . Streptococci was isolated in 15 eyes, Pseudomonas in 3 eyes, and Candida in 1 eye. The visual outcomes at three months were significantly worse in Group A (LogMAR 1.77±1.06) compared to Group B (LogMAR 0.65±0.68)(p0.05).Central corneal involvement, vitreous/ iris incarceration and PCR were important risk factors for development of PTE in children.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0997233927a3903ed450822056a88fca https://doi.org/10.1080/09273948.2021.1928237 Zobrazit plný text záznamu