First episode of preschool wheeze requiring hospitalization:a prospective study on the chance of recurrence and associated factors
| Autor: | Karaked Chantawarangul, Suchada Sritippayawan, Jitladda Deerojanawong |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Immunology Prevalence medicine.disease_cause Recurrence Risk Factors Epidemiology medicine Hypersensitivity Immunology and Allergy Humans Prospective Studies Risk factor Prospective cohort study Respiratory Sounds First episode business.industry Incidence (epidemiology) Incidence Infant Aeroallergen General Medicine Thailand Hospitalization Child Preschool Observational study Female business |
| Zdroj: | Asian Pacific journal of allergy and immunology. 36(4) |
| ISSN: | 0125-877X |
| Popis: | Background Although wheezing is very common in preschoolers, epidemiologic studies in Thailand are quite limited. The likelihood of having a second wheezing episode following the first attack remains unclearly established. Objectives This study aims to investigate the incidence of recurrent wheezing in preschool children presenting with first wheezing episode and identify the associated factors. Methods The study is an observational prospective study conducted at the inpatient pediatric department. Patients admitted with first episode of wheezing were followed up as an outpatient approximately one week after hospital discharge and subsequently followed up by telephone 3-monthly with a structured questionnaire seeking information concerning recurrent wheezing, defined as having a second wheezing episode requiring bronchodilator within a 1-year period. Results The total of 97 patients, aged 6 months to 5 years, were recruited from June 2014 to November 2015. Thirty-five patients were excluded because of inaccessibility for telephone follow-up. Amongst the remaining 62 patients, twenty-eight (45.2%) had recurrent wheezing within one year. The mean lapse duration was 4.7 ± 3.7 months after the first episode. Having an allergic sensitization to aeroallergen was a risk factor for recurrent wheezing (OR 2.48, 95%CI 1.81-3.4). Although not statistically significant, having an allergic sensitization to food seems to be another related factor (OR 2.36, 95%CI 1.75-3.18). Conclusion The recurrent rate of wheezing was 45%, which was considerably significant. Allergic sensitization to aeroallergen might increase the risk. These patients should be followed up, especially within the first year after their first wheezing episode. |
| Databáze: | OpenAIRE |
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