Inhibition of Sodium Intestinal Transport and Mucosal (Na+-K+)-ATPase in Experimental Fanconi Syndrome
| Autor: | Ramon Alfonso Exeni, Francisco J. de Rosas, Fima Lifshitz, Raul A. Wapnir, Melinda McVicar |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Male
medicine.medical_specialty Sodium Potassium chemistry.chemical_element Absorption (skin) General Biochemistry Genetics and Molecular Biology Intestinal mucosa Internal medicine medicine Animals Amino Acids Intestinal Mucosa Na+/K+-ATPase Adenosine Triphosphatases chemistry.chemical_classification Maleates Glucose transporter Fanconi syndrome Biological Transport Fanconi Syndrome medicine.disease Rats Amino acid Glucose Jejunum Endocrinology chemistry |
| Zdroj: | Experimental Biology and Medicine. 150:517-520 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-150-39068 |
| Popis: | SummaryThe administration of 1.5 or 9.0 mmoles/kg ip of maleate to rats induced, in addition to renal alterations similar to those occurring in the Fanconi syndrome, a decline in the intestinal mucosa (Na+-K+)-ATPase with a simultaneous decrease in sodium intestinal transport and an increase in potassium absorption. Further differences in the behavior of the two electrolytes were observed when the concentration of sodium in the perfusates was altered. No changes occurred in amino acid or glucose transport in experimental animals. |
| Databáze: | OpenAIRE |
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