Relation of pharmacopenile duplex ultrasonography parameters and glycated hemoglobin (HbA1c) in diabetic patients with erectile dysfunction
| Autor: | Emad Eldien Kamal, Reham I El-Mahdy, Mona M. Soliman, Mohammed Essam M. Ali, Ahmed M. El-Sayed, Aya Y. Badran, Mohamed Zidan Mohamed |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Duplex ultrasonography medicine.medical_specialty Urology 030232 urology & nephrology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Erectile Dysfunction Diabetes mellitus Diabetes Mellitus Medicine Humans Medical history Poor glycaemic control Ultrasonography Glycated Hemoglobin 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Erectile function Middle Aged medicine.disease Erectile dysfunction Reproductive Medicine chemistry Glycated hemoglobin business Lipid profile Penis |
| Zdroj: | Revista internacional de andrologia. 20(1) |
| ISSN: | 1698-0409 |
| Popis: | Introduction and objectives Erectile dysfunction (ED) is one of the main threats in diabetic patients. This research aimed to assess the relationship between glycated hemoglobin (HbA1c) level and pharmacopenile duplex ultrasonography (PPDU) indices in diabetic patients with ED. Materials and methods A total of 130 males with ED were recruited (100 had diabetes mellitus (DM) and 30 did not as control). The International Index of Erectile Function (IIEF) was used to evaluate patients for ED. Measurement of HbA1c, lipid profile and assessment of erectile function using PPDU were performed. All participants were assessed to take the medical history. Results The mean age ± SD was 53.8 ± 8.9 and 53.6 ± 2.8 years for patients and controls, respectively. Patients had variable grades of ED: mild in 20%, mild to moderate in 32.3%, moderate in 35.3%, and severe in 12.3%. A significant association was found between the existence of DM and a deprived response to intracorporeal injection (ICI), rising end-diastolic velocity (EDV), and reducing resistance index (RI) values. Comparing all diabetic groups according to HbA1c with controls, a significant relationship was found in; severity of IIEF-5 score, poor response to ICI, decreased peak systolic velocity (PSV) at 10 min, increased EDV at 10, 20 min and decreased RI at 10, 20 min. A significant relationship was found between smoking, dyslipidaemia, and decreased PSV at 10, 20 min and decreased increment ratio. However, a non-significant relationship was observed between age, type of DM and PPDU parameters. Conclusion Poor glycaemic control of DM is associated with an increase in EDV and decrease in RI, and PSV of PPDU. |
| Databáze: | OpenAIRE |
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