Temperature monitoring and temperature-driven irrigated radiofrequency energy titration do not prevent thermally induced esophageal lesions in pulmonary vein isolation: A randomized study controlled by esophagoscopy before and after catheter ablation
| Autor: | Dirk Grosse Meininghaus, Tobias Kleemann, Kai Blembel, Claudia Waniek, Juergen Kruells-Muench, J. Christoph Geller, Helmut Ernst |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_treatment Catheter ablation 030204 cardiovascular system & hematology Esophageal lesions law.invention Pulmonary vein Body Temperature 03 medical and health sciences 0302 clinical medicine Esophagus Randomized controlled trial law Physiology (medical) Atrial Fibrillation medicine Clinical endpoint Humans 030212 general & internal medicine Intraoperative Complications Aged Monitoring Physiologic Retrospective Studies medicine.diagnostic_test business.industry Esophagogastroduodenoscopy Temperature Atrial fibrillation medicine.disease Atrioesophageal fistula Pulmonary Veins Catheter Ablation Female Esophagoscopy Cardiology and Cardiovascular Medicine Nuclear medicine business Follow-Up Studies |
| Zdroj: | Heart rhythm. 18(6) |
| ISSN: | 1556-3871 |
| Popis: | Endoscopically detected esophageal lesions (EDELs) are common following pulmonary vein isolation (PVI) and may progress to atrioesophageal fistula (AEF).The purpose of this study was to study (1) the benefit of luminal esophageal temperature (LET) monitoring and (2) the impact of esophagogastroduodenoscopy (EGD) in detecting EDEL and defining pre-existing lesions. The primary endpoint was the number of ablation-induced lesions.Patients with atrial fibrillation were randomized to PVI with LET monitoring (LET[+]) or without LET monitoring (LET[-]). All patients underwent EGD before and after PVI. Ablation power at the left atrial (LA) posterior wall was limited to 25 W in all patients and was titrated to a minimum of 10 W guided by esophageal temperature in the LET[+] group.Eighty-six patients (age 67 ± 10 years; 57% male) were included (44 LET[+], 42 LET[-]). PVI was achieved in all, and additional linear LA lesions were done in 50%. Eight patients developed EDEL (6 LET[+], 2 LET[-]; P = NS). Whereas LET41°C did not differentiate with regard to EDEL formation, temperature overshooting ≥42°C was associated with a higher risk for new EDEL. Two-thirds of patients showed incidental findings (esophagitis, gastric ulcer) on preprocedural EGD; 8 esophageal lesions were pre-existing. Four patients in the LET[+] group developed epistaxis following insertion of the probe.Monitoring of LET does not prevent ablation-induced esophageal lesions. Patients without temperature surveillance were not at higher risk, but temperatures ≥42°C were associated with increased likelihood of mucosal lesions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|