Bone Disease in Patients with Ehlers–Danlos Syndromes
Autor: | Frank Rauch, Shuaa Basalom |
---|---|
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Fracture risk medicine.medical_specialty Bone disease Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Fractures Bone 03 medical and health sciences Absorptiometry Photon 0302 clinical medicine medicine Humans Mass Screening In patient Bone mineral business.industry medicine.disease Dermatology Spine Bone Diseases Metabolic 030104 developmental biology Ehlers–Danlos syndrome Orthopedic surgery Cohort Osteoporosis Ehlers-Danlos Syndrome business Bone mass |
Zdroj: | Current Osteoporosis Reports. 18:95-102 |
ISSN: | 1544-2241 1544-1873 |
DOI: | 10.1007/s11914-020-00568-5 |
Popis: | To summarize the bone findings, mainly bone mass and fracture risk, in Ehlers–Danlos syndromes (EDS). Low bone mineral density and fractures seem to be frequent in some of the rare EDS types (kyphoscoliotic, arthrochalasia, spondylodysplastic, and classic-like EDS). For the more prevalent hypermobile and classic EDS types, some case–control studies found mildly decreased bone mineral density, but it was not clear that fracture rates were increased. Nevertheless, abnormalities in vertebral shape seem to be common in classical and hypermobile EDS types. In a cohort of individuals with EDS followed since birth, no fractures were observed during infancy. Bone mineral density varies widely among the different types of EDS, and vertebral abnormalities seem to be common in classical and hypermobile EDS. It might be justified to perform spine radiographs and bone mineral density assessments in newly diagnosed EDS. |
Databáze: | OpenAIRE |
Externí odkaz: |