Juvenile xanthogranuloma occurring in the oral cavity: case report and histopathological findings
Autor: | Kazushi Imai, Etsuhide Yamamoto, Shuichi Kawashiri, Kiyomasa Nakagawa, Shigehiro Kumagai |
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Rok vydání: | 1997 |
Předmět: |
Male
Cytoplasm Cancer Research medicine.medical_specialty Pathology Juvenile xanthogranuloma Cytoplasmic Granules Antibodies Pathology and Forensic Medicine Lesion Dermis Stroma Humans Medicine Oral mucosa Child Histiocyte Palate business.industry Macrophages S100 Proteins Antibodies Monoclonal Histiocytes Nodule (medicine) Anatomy Fibroblasts medicine.disease Lipids Microscopy Electron medicine.anatomical_structure Otorhinolaryngology Periodontics Muramidase Histopathology Oral Surgery medicine.symptom Mouth Diseases business Xanthogranuloma Juvenile Cell Division Foam Cells Follow-Up Studies |
Zdroj: | Journal of Oral Pathology and Medicine. 26:484-487 |
ISSN: | 1600-0714 0904-2512 |
DOI: | 10.1111/j.1600-0714.1997.tb00021.x |
Popis: | Juvenile xanthogranuloma is commonly seen in the dermis, and only very rarely develops in the oral mucosa. Here were report a case that occurred in the anterior palate of a 9-year-old boy. The lesion appeared as a dark red and well-defined nodule measuring 12 x 14 mm. Histologically, it consisted of a proliferation of histiocytes and fibroblastic stroma intermingled with foamy cells. Many lipid droplets without limiting membrane were observed in the cytoplasm under electron microscopy, but no Langerhans' cell granules were observed. The proliferative histiocytes were positive for lysozyme and macrophage HAM56 under immunohistochemical observation, but not for S-100 protein. From these findings, the lesion was diagnosed as juvenile xanthogranuloma. The post-operative course, now amounting to 7 years, has been uneventful. |
Databáze: | OpenAIRE |
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