GC-MS Analysis of β-Carotene Ethenolysis Products and their Synthesis as Potentially Active Vitamin A Analogues

Autor:	I. Jermacz, Jadwiga Maj, Jacek W. Morzycki, Agnieszka Wojtkielewicz
Rok vydání:	2008
Předmět:	Vitamin chemistry.chemical_classification Ethenolysis Double bond Chemistry Health Toxicology and Mutagenesis medicine.medical_treatment Carotene Regioselectivity chemistry.chemical_element Nanotechnology β-Carotene Toxicology Cleavage (embryo) Article Catalysis Ruthenium Cross-Metathesis chemistry.chemical_compound medicine Organic chemistry Vitamin A Derivatives
Zdroj:	Toxicology Mechanisms and Methods
ISSN:	1537-6524 1537-6516
Popis:	beta-Carotene ethenolysis under promotion of well-defined ruthenium catalysts were examined as a novel method of synthesis of vitamin A derivatives. Efficient reaction was promoted by the second-generation Hoveyda catalyst. The products of ethenolysis in positions C15-C15', C11-C12, and C9-C10 were detected, but cleavage of the C11-C12 double bond predominated. Even better regioselectivity at this position was observed for cross-metathesis between beta-carotene and functionalized alkenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0965b98f2a8a99e98145c3e34f2d9be9 https://doi.org/10.1080/15376510701623656 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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