Preexisting Heterotypic Ligand-blocking Antibody Does Not Protect Against Genogroup II Norovirus Episodes in Young Children

Autor: Sylvia Becker-Dreps, Paul D Brewer-Jensen, Fredman González, Yaoska Reyes, Michael L Mallory, Lester Gutiérrez, Nadja A Vielot, Marta Diez-Valcarce, Jan Vinjé, Ralph S Baric, Lisa C Lindesmith, Filemon Bucardo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: J Pediatric Infect Dis Soc
Popis: A birth cohort design was used to understand whether heterotypic ligand-blocking norovirus antibodies provide cross-protection within the GII genogroup. We found that almost one-half of children who experienced a norovirus GII episode had preexisting antibodies heterotypic to the infecting genotype; therefore, these antibodies did not provide cross-protection.
Databáze: OpenAIRE