Inflammation-Based Score (Combination of Platelet Count and Neutrophil-to-Lymphocyte Ratio) Predicts Pharyngocutaneous Fistula After Total Laryngectomy

Autor: Shin Matsumoto, Masahiro Nakayama, Masahiko Gosho, Bungo Nishimura, Kuniaki Takahashi, Tomonori Yoshimura, Masamitsu Senarita, Hirotatsu Ohara, Hiromitsu Akizuki, Tetsuro Wada, Keiji Tabuchi
Rok vydání: 2021
Předmět:
Zdroj: The LaryngoscopeBIBLIOGRAPHY. 132(8)
ISSN: 1531-4995
1582-1587
Popis: Postoperative complications may depend on the systemic inflammatory response. We evaluated the predictive potential of the combination of platelet count and neutrophil-to-lymphocyte ratio (COP-NLR) for the incidence of pharyngocutaneous fistula (PCF) in patients who have undergone total laryngectomy.Retrospective cohort study.Patients who underwent total laryngectomy between 2000 and 2020 were recruited from four hospitals. The correlations between the incidence of PCF and several risk factors, including the COP-NLR, were examined. Patients with both elevated platelet count and elevated neutrophil-to-lymphocyte ratio (NLR) were categorized as COP-NLR 2, and patients with either one or no abnormal values of both parameters were assigned as COP-NLR 1 and COP-NLR 0, respectively.A total of 235 patients were identified. The overall incidence of PCF was 12.3%. The cut-off value for NLR before surgery was set at 3.95 (sensitivity = 58.6%, specificity = 69.4%, area under the curve [AUC] = 0.635), and the platelet count was set at 320 × 10COP-NLR is a novel predictive factor for the development of PCF in patients undergoing total laryngectomy.4 Laryngoscope, 132:1582-1587, 2022.
Databáze: OpenAIRE
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