Cutaneous T-cell Lymphoma
| Autor: | Glass Lf, C Yag-Howard, Jane L. Messina, J Dalton, Neil A. Fenske, KL Keller |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
business.industry Helper T lymphocyte Cutaneous T-cell lymphoma Treatment options Hematology General Medicine Disease medicine.disease 030226 pharmacology & pharmacy Dermatology Lymphoma 03 medical and health sciences 0302 clinical medicine Immunophenotyping Oncology hemic and lymphatic diseases 030220 oncology & carcinogenesis Gene Rearrangement Analysis Epidemiology Medicine business |
| Zdroj: | Cancer Control. 5:11-18 |
| ISSN: | 1073-2748 |
| DOI: | 10.1177/107327489800500101 |
| Popis: | Background: Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed of malignant helper T lymphocytes. An accurate diagnosis of early CTCL is difficult because of the varied clinical and histologic expressions of the disease. Methods: The authors review the epidemiology, possible risk factors, clinical manifestations, diagnostic techniques, staging, prognosis, and treatment options for CTCL. Results: The varied and often nonspecific clinical and histologic presentations of CTCL may delay diagnosis and staging, thus necessitating further studies such as immunophenotyping flow cytometry, and T-cell receptor gene rearrangement analysis. Conclusions: A multidisciplinary approach to the diagnosis, staging, and treatment of CTCL assists in optimizing outcomes from management of patients with this disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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