| Autor: |
Byrne-Hoffman, Christina N., Wentao Deng, McGrath, Owen, Wang, Peng, Rojanasakul, Yon, Klinke, David J. |
| Rok vydání: |
2020 |
| DOI: |
10.6084/m9.figshare.12367859 |
| Popis: |
Additional file 4 Supplemental Figure S4: Diagnostics for Markov Chain Monte Carlo estimates of the posterior distribution in the Imatinib EC50 and IL12 effect (α) estimated from ATPlite assay results using Melan-A cells. The traces for the initial 10000 steps (A and B) and full length (C and D) of three independent chains (colored in black, blue, and red, respectively) with over disperse starting points. (E) The Gelman-Rubin potential scale reduction factor (PSRF) was used to assess convergence of the Markov Chains to the posterior distribution in the Imatinib EC50 (left panel) and IL12 effect α (right panel), where a value of less than 1.2 indicated that the chains have converged to sampling the posterior distribution. The MCMC chains converged after less than 50,000 steps. (F) New steps in the Markov Chain were proposed using a normally distributed random number generator with a mean of zero and adjusted standard deviation such that the acceptance fraction was 0.2. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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