Increased atrial contraction contribution to left ventricular filling during early septic shock
| Autor: | Ana Del Rio Lechuga, Anselmo Gil Cano, Manuel Ignacio Monge García, Nick Fletcher |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Resuscitation Contraction (grammar) Systole Cardiac Volume Hemodynamics Critical Care and Intensive Care Medicine Ventricular Function Left Sepsis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans cardiovascular diseases Ejection fraction business.industry Septic shock 030208 emergency & critical care medicine Middle Aged medicine.disease Shock Septic Icu admission Intensive Care Units 030228 respiratory system Echocardiography Case-Control Studies cardiovascular system Cardiology Atrial Function Left Female Ventricular filling business |
| Zdroj: | Journal of critical care. 54 |
| ISSN: | 1557-8615 |
| Popis: | To assess the atrial systolic function and the contribution of atrial contraction to left ventricular (LV) filling in septic shock patients as compared with healthy volunteers.Twenty-seven septic patients evaluated during first 48 h of ICU admission and compared with 27 healthy volunteers. Left atrial (LA) contraction contribution to LV filling was calculated as the active emptying atrial volume/LV end-diastolic volume. Atrial systolic function was evaluated with the atrial kinetic force [LAKE = 0.5 × blood density × LVVLV ejection fraction was lower in septic patients than in control group: 51 ± 14%vs 60 ± 6% (p 0.01). Contribution of LA contraction to LV preload was greater in septic patients than in normal subjects (26.7 ± 11.3% vs 15.9 ± 5.9%, p 0.001), even if adjusted for age (0.49 ± 0.19 vs 0.35 ± 0.13, p = 0.004). LAKE and LASF were also significantly larger in septic patients than in normal subjects (21.8 ± 9.1 vs 7.3 ± 3 kdynes·cm, p 0.001; 16.1 ± 11.7 vs 9.8 ± 4.3 kdynes, p = 0.048, respectively), and remained unchanged during the next 48 h.In septic shock patients, LA systolic function increased and greatly contributed to support LV filling. These results highlight the role of preserving atrial contraction on the hemodynamic resuscitation in early septic shock. |
| Databáze: | OpenAIRE |
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