Long-term outcome of sacral neuromodulation for chronic refractory constipation

Autor: Michael A. Kamm, Claes Johansson, C. G. M. I. Baeten, Søren Laurberg, Carolynne J. Vaizey, Yasuko Maeda, Klaus E. Matzel, Harald R. Rosen
Přispěvatelé: RS: NUTRIM - R2 - Liver and digestive health, Surgery, RS: NUTRIM - R2 - Gut-liver homeostasis
Rok vydání: 2017
Předmět:
Male
Constipation
Severity of Illness Index
law.invention
DOUBLE-BLIND
0302 clinical medicine
Quality of life
Randomized controlled trial
law
Prospective Studies
Defecation
Prospective cohort study
Gastroenterology
Middle Aged
Colorectal surgery
Electrodes
Implanted
Treatment Outcome
030220 oncology & carcinogenesis
Female
Original Article
030211 gastroenterology & hepatology
medicine.symptom
Life Sciences & Biomedicine
Adult
Sacrum
medicine.medical_specialty
Adolescent
Sacral nerve stimulation
Electric Stimulation Therapy
CONTROLLED-TRIAL
CONTROLLED CROSSOVER
Time
Young Adult
03 medical and health sciences
Severity of illness
Journal Article
medicine
Humans
NERVE-STIMULATION
Aged
Science & Technology
Gastroenterology & Hepatology
business.industry
SLOW TRANSIT CONSTIPATION
Sacral neuromodulation
1103 Clinical Sciences
EFFICACY
Surgery
IDIOPATHIC CONSTIPATION
BIOFEEDBACK
Chronic Disease
Quality of Life
business
Follow-Up Studies
Abdominal surgery
Zdroj: Techniques in coloproctology, 21(4), 277-286. Springer
Techniques in Coloproctology
Maeda, Y, Kamm, M A, Vaizey, C J, Matzel, K E, Johansson, C, Rosen, H, Baeten, C G & Laurberg, S 2017, ' Long-term outcome of sacral neuromodulation for chronic refractory constipation ', Techniques in Coloproctology (Online), vol. 21, no. 4, pp. 277-286 . https://doi.org/10.1007/s10151-017-1613-0
ISSN: 1128-045X
1123-6337
DOI: 10.1007/s10151-017-1613-0
Popis: Purpose Sacral neuromodulation has been reported as a treatment for severe idiopathic constipation. This study aimed to evaluate the long-term effects of sacral neuromodulation by following patients who participated in a prospective, open-label, multicentre study up to 5 years.Methods Patients were followed up at 1, 3, 6, 12, 24, 36, 48 and 60 months. Symptoms and quality of life were assessed using bowel diary, the Cleveland Clinic constipation score and the Short Form-36 quality-of-life scale.Results Sixty-two patients (7 male, median age 40 years) underwent test stimulation, and 45 proceeded to permanent implantation. Twenty-seven patients exited the study (7 withdrawn consent, 7 loss of efficacy, 6 site-specific reasons, 4 withdrew other reasons, 2 lost to follow-up, 1 prior to follow-up). Eighteen patients (29%) attended 60-month follow-up. In 10 patients who submitted bowel diary, their improvement of symptoms was sustained: the number of defecations per week (4.1 +/- 3.7 vs 8.1 +/- 3.4, mean +/- standard deviation, p Conclusion Benefit from sacral neuromodulation in the long-term was observed in a small minority of patients with intractable constipation. The results should be interpreted with caution given the high dropout and complication rate during the follow-up period.
Databáze: OpenAIRE
Externí odkaz: