Infective Endocarditis Following Transcatheter Aortic Valve Replacement
Autor: | David Messika-Zeitoun, Marcos Antonio Marino, Vincent Auffret, Nikolaj Ihlemann, Hasan Jilaihawi, Mohamed Abdel-Wahab, Oliver Husser, Thomas Walther, Alec Vahanian, Harindra C. Wijeysundera, Luis Nombela-Franco, Raj Makkar, Lars Søndergaard, Marina Urena, John G. Webb, Axel Linke, Ugolino Livi, Costanza Pellegrini, Josep Rodés-Cabau, Luis A. Carvalho, Henrique Barbosa Ribeiro, Francesco Rosato, Antonio J. Muñoz-García, Alberto San Roman, Norman Mangner, Claudia Fiorina, Enrique Gutiérrez-Ibañes, Stefan Stortecky, Hervé Le Breton, Asim N. Cheema, Jan Malte Sinning, Samir R. Kapadia, Azeem Latib, Fabian Nietlispach, Eric Durand, Marco Barbanti, Hélène Eltchaninoff, Antonio L. Bartorelli, Won-Keun Kim, José Armando Mangione, Antonio Miceli, Howard C. Herrmann, John Lisko, Maria Cristina Ferreira, Juan C. Castillo, Dominique Himbert, Alexandre Abizaid, Susheel Kodali, Rishi Puri, Luca Testa, Ignacio J. Amat-Santos, Martin B. Leon, Vicenç Serra, Guglielmo Mario Actis Dato, Jean Bernard Masson, Valter C. Lima, Ander Regueiro, Pedro A. Lemos, Vinicius Esteves, Julio Andrea, Stamatios Lerakis, Fabio Sandoli de Brito, Thomas Pilgrim, Didier Tchetche |
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Rok vydání: | 2019 |
Předmět: |
Balloon Valvuloplasty
Male Reoperation medicine.medical_specialty Prosthesis-Related Infections Time Factors Transcatheter aortic medicine.medical_treatment Clinical Decision-Making registry Prosthesis Design Balloon Risk Assessment Transcatheter Aortic Valve Replacement Valve replacement Aortic valve replacement Risk Factors 80 and over medicine Humans Endocarditis Registries Device Removal Aged Retrospective Studies endocarditis incidence transcatheter aortic valve replacement Aged 80 and over Aortic Valve Aortic Valve Stenosis Endocarditis Bacterial Female Incidence Patient Selection Treatment Outcome Heart Valve Prosthesis Self expandable business.industry Bacterial medicine.disease Surgery Infective endocarditis Cardiology and Cardiovascular Medicine business |
Zdroj: | Circulation: Cardiovascular Interventions. 12 |
ISSN: | 1941-7632 1941-7640 |
Popis: | Background: No data exist about the characteristics of infective endocarditis (IE) post-transcatheter aortic valve replacement (TAVR) according to transcatheter valve type. We aimed to determine the incidence, clinical characteristics, and outcomes of patients with IE post-TAVR treated with balloon-expandable valve (BEV) versus self-expanding valve (SEV) systems. Methods: Data from the multicenter Infectious Endocarditis After TAVR International Registry was used to compare IE patients with BEV versus SEV. Results: A total of 245 patients with IE post-TAVR were included (SEV, 47%; BEV, 53%). The timing between TAVR and IE was similar between groups (SEV, 5.5 [1.2–15] months versus BEV, 5.3 [1.7–11.4] months; P =0.89). Enterococcal IE was more frequent in the SEV group (36.5% versus 15.4%; P P =0.01; valve leaflet, SEV, 23.9%; BEV, 38.5%; P =0.01). BEV recipients had a higher rate of stroke/systemic embolism (20.0% versus 8.7%, adjusted OR: 2.46, 95% CI: 1.04–5.82, P =0.04). Surgical explant of the transcatheter valve (SEV, 8.7%; BEV, 13.8%; P =0.21), and in-hospital death at the time of IE episode (SEV, 35.6%; BEV, 37.7%; P =0.74) were similar between groups. After a mean follow-up of 13±12 months, 59.1% and 54.6% of the SEV and BEV recipients, respectively, had died ( P =0.66). Conclusions: The characteristics of IE post-TAVR, including microorganism type, vegetation location, and embolic complications but not early or late mortality, differed according to valve type. These results may help to guide the diagnosis and management of IE and inform future research studies in the field. |
Databáze: | OpenAIRE |
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