Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
| Autor: | Camila Bonin Pinto, Faddi Ghassan Saleh Velez, Emma S. Bailin, Marionna Münger, Lotfi B. Merabet, Beatriz Teixeira Costa, Andrew Ellison, Nadia Bolognini, David Crandell, Felipe Fregni |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
030506 rehabilitation medicine.medical_specialty Scanner medicine.medical_treatment General Chemical Engineering Video Recording General Biochemistry Genetics and Molecular Biology Article 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Neuroimaging Amputees Functional neuroimaging Neuroplasticity Medicine Humans Projection (set theory) Neural correlates of consciousness medicine.diagnostic_test General Immunology and Microbiology business.industry General Neuroscience Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging Amputation Phantom Limb 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | Journal of visualized experiments : JoVE. (146) |
| ISSN: | 1940-087X |
| Popis: | Mirror therapy (MT) has been proposed as an effective rehabilitative strategy to alleviate pain symptoms in amputees with phantom limb pain (PLP). However, establishing the neural correlates associated with MT therapy have been challenging given that it is difficult to administer the therapy effectively within a magnetic resonance imaging (MRI) scanner environment. To characterize the functional organization of cortical regions associated with this rehabilitative strategy, we have developed a combined behavioral and functional neuroimaging protocol that can be applied in participants with a leg amputation. This novel approach allows participants to undergo MT within the MRI scanner environment by viewing real-time video images captured by a camera. The images are viewed by the participant through a system of mirrors and a monitor that the participant views while lying on the scanner bed. In this manner, functional changes in cortical areas of interest (e.g., sensorimotor cortex) can be characterized in response to the direct application of MT. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|