Safety of Chemical DVT Prophylaxis in Severe Traumatic Brain Injury with Invasive Monitoring Devices
| Autor: | Lacey Avila, Ali Seifi, Brian Hernandez, Paolo Mendez-Gomez, Bradley A. Dengler, Ramesh Grandhi, Amanda Chavez, Joel E. Michalek |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Traumatic brain injury Deep vein Critical Care and Intensive Care Medicine law.invention 03 medical and health sciences 0302 clinical medicine law Brain Injuries Traumatic medicine Humans Hospital Mortality Intraparenchymal hemorrhage Cerebral Hemorrhage Retrospective Studies Venous Thrombosis business.industry Heparin Incidence (epidemiology) Anticoagulants 030208 emergency & critical care medicine Retrospective cohort study medicine.disease Intensive care unit Thrombosis Neurophysiological Monitoring Venous thrombosis Intensive Care Units medicine.anatomical_structure Anesthesia Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Neurocritical care. 25(2) |
| ISSN: | 1556-0961 |
| Popis: | Patients with traumatic brain injuries (TBIs) have an increased risk of developing a deep vein thrombosis (DVT), but the risk of hemorrhage expansion with intracranial monitoring devices remains unknown. We sought to determine the safety of chemical DVT prophylaxis in severe TBI patients with invasive intracranial pressure monitors. We retrospectively reviewed all patients with severe TBI admitted to the neurosurgical intensive care unit of a large tertiary care center over a three-year period. 155 patients were included with an incidence of DVT of 12 %. The median length of time to a stable head CT was 2 days, and the median time to initiation of chemical DVT prophylaxis was 3.6 days. The odds of DVT increased with intraparenchymal hemorrhage [OR 7.21, 95 % CI (1.43–36.47), p = 0.0169], non-White ethnicity [OR 7.86, 95 % CI (1.23–50.35), p = 0.0295], female gender [OR 13.93, 95 % CI (2.47–78.73), p = 0.0029], smoking [OR 4.32, 95 % CI (1.07–17.51), p = 0.0405], no anticoagulation [OR 25.39, 95 % CI (4.26–151.48), p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink