Comparison of organ-specific-radiation dose levels between 70 kVp perfusion CT and standard tri-phasic liver CT in patients with hepatocellular carcinoma using a Monte-Carlo-Simulation-based analysis platform
| Autor: | Sonja Sudarski, Holger Haubenreisser, C Hagelstein, Thomas Henzler, Stefan O. Schoenberg, Mathias Meyer, Joshua Gawlitza |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty Hepatocellular carcinoma lcsh:R895-920 Monte Carlo method Article 030218 nuclear medicine & medical imaging Liver ct 03 medical and health sciences 0302 clinical medicine Organ specific Dynamic volume perfusion CT Medicine Radiology Nuclear Medicine and imaging In patient CT protocol business.industry Radiation dose medicine.disease Dose 030220 oncology & carcinogenesis Radiology business Nuclear medicine Perfusion |
| Zdroj: | European Journal of Radiology Open, Vol 3, Iss, Pp 95-99 (2016) European Journal of Radiology Open |
| ISSN: | 2352-0477 |
| Popis: | Purpose: The aim of this study was to systematically compare organ-specific-radiation dose levels between a radiation dose optimized perfusion CT (dVPCT) protocol of the liver and a tri-phasic standard CT protocol of the liver using a Monte-Carlo-Simulation-based analysis platform. Methods and materials: The complete CT data of 52 patients (41 males; mean age 65 ± 12) with suspected HCC that underwent dVPCT examinations on a 3rd generation dual-source CT (Somatom Force, Siemens) with a dose optimized tube voltage of 70 kVp or 80 kVp were exported to an analysis platform (Radimetrics, Bayer). The dVPCT studies were matched with a reference group of 50 patients (35 males; mean age 65 ± 14) that underwent standard tri-phasic CT (sCT) examinations of the liver with 130 kVp using the calculated water-equivalent-diameter of the patients. The analysis platform was used for the calculation of the organ-specific effective dose (ED) as well as global radiation-dose parameters (ICRP103). Results: The organ-specific ED of the dVPCT protocol was statistically significantly lower when compared to the sCT in 14 of 21, and noninferior in a total of 18 of 21 examined items (all p |
| Databáze: | OpenAIRE |
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