Supplemental Tables 1-5, Supplemental Figure 1-2 from Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and ZEB1-Binding Sites that Influence the Cellular Response to Paclitaxel

Autor: Minjie Wei, Huizhe Wu, Olufunmilayo I. Olapade, Jianjun Chen, Yong Liu, Feng Jin, Weifan Yao, Haishan Zhao, Jing Zhang, Binbin Wei, Yilin Wang, Miao He, Shu Guan, Xiaoyun Hu, Xiaolan Deng, Qiuchen Chen
Rok vydání: 2023
DOI: 10.1158/1541-7786.22512960.v1
Popis: Table S1. Frequencies of mTOR promoter polymorphisms in patients with breast cancer and healthy controls Table S2. Frequency distribution of mTOR haplotypes and their associations with the risk of developing breast cancer Table S3. Association of mTOR haplotypes with clinicopathological parameters in patients with breast cancer Table S4. Association of mTOR polymorphisms with clinicopathological parameters in patients with breast cancer Table S5. Association of mTOR polymorphisms with therapeutic response to neoadjuvant chemotherapy (n=131) Figure S1. The impact of forced expression of pcmTOR-Ht1 or pcmTOR-Ht2 on cell proliferation and cell cycle and chemoresistance to PTX in MCF7/PTX cells. Figure S2. Plasma concentration of PTX detection by using UPLC-MS/MS method.
Databáze: OpenAIRE