Dewerin and gilbertionol two new secondary metabolites from the stem bark of Gilbertiodendron dewevrei (De Wild) J. Leonard
| Autor: | Norbert Sewald, Fongang Fotsing Yannick Stéphane, Bruno Ndjakou Lenta, Fatma Kaaniche, Bankeu Kezetas Jean Jules, Isabelle Kamga Mawabo, Silvère Ngouela, Dietagoum Madjouka Stephanie |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Stem bark
biology Traditional medicine 010405 organic chemistry Organic Chemistry Plant Science biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry Gilbertiodendron dewevrei 010404 medicinal & biomolecular chemistry Phytochemical Caesalpinioideae |
| Zdroj: | Natural Product Research. 36:214-222 |
| ISSN: | 1478-6427 1478-6419 |
| Popis: | The phytochemical investigation of the methanol extract of the stem bark of Gilbertiodendron dewevrei led to the isolation of two new secondary metabolites, 5,7-dihydroxy-4′-methoxyisoflavan-2,4-dione (1) and 23-hydroxy-2-tricosanone (2) along with 19 known compounds (3–21). The structure of these compounds were established by interpretation of their spectral data, mainly HR-TOFESIMS, 1 D NMR (1H, 13C and DEPT) and 2 D NMR (1H–1H COSY, HSQC, HMBC, and NOESY), and by comparison with those reported in the literature. The methanol extract and some isolates were screened for their antiradical, antibacterial, and inhibitory properties against acetylcholinesterase. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|