The associations among Helicobacter pylori infection, white blood cell count and nonalcoholic fatty liver disease in a large Chinese population
| Autor: | Yuling Tong, Zhenya Song, Jinghua Wang, Yingying Yu, Jian-ting Cai |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male nonalcoholic fatty liver disease medicine.medical_specialty China 13C-urea breath test Observational Study Gastroenterology Helicobacter Infections 03 medical and health sciences Leukocyte Count 0302 clinical medicine Insulin resistance Non-alcoholic Fatty Liver Disease Risk Factors Internal medicine White blood cell Nonalcoholic fatty liver disease Odds Ratio Prevalence Medicine Blood test Humans Urea cross-sectional study Breath test biology medicine.diagnostic_test Helicobacter pylori business.industry General Medicine Odds ratio Middle Aged biology.organism_classification medicine.disease medicine.anatomical_structure Cross-Sectional Studies Logistic Models Breath Tests 030220 oncology & carcinogenesis Multivariate Analysis 030211 gastroenterology & hepatology Female business Body mass index Research Article white blood cell count |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Reported relationships among Helicobacter pylori infection, white blood cell (WBC) count and nonalcoholic fatty liver disease (NAFLD) are inconsistent and controversial. We, therefore, conducted a cross-sectional study to investigate the associations among the presence of NAFLD, WBC count and H pylori infection, as diagnosed using the 13C-urea breath test (UBT). This study included 20,389 subjects enrolled at the International Health Care Center of the Second Affiliated Hospital of the Zhejiang University School of Medicine from January 2015 to December 2015. All participants underwent a 13C-UBT for the diagnosis of H pylori infection and ultrasonography for NAFLD as well as a blood test to determine WBC count. Multivariate logistic regression was then performed to evaluate the relationship among H pylori infection, WBC count and NAFLD. H pylori infection was detected in 38.49% (7,848/20,389) of the subjects via the UBT, and NAFLD was present in 37.24% (7,592/20,389) of the subjects. The prevalence of H pylori infection was higher in the NAFLD group than in the control group (41.25% vs 36.85%, P |
| Databáze: | OpenAIRE |
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