Risk factors for poor outcomes and therapeutic strategies for seasonal and pandemic influenza
Autor: | Mitchell Hamele, Heather Siefkes, W. Bradley Poss, Krow Ampofo |
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Rok vydání: | 2015 |
Předmět: |
medicine.medical_specialty
biology business.industry Antigenic shift Critical Care and Intensive Care Medicine medicine.disease Intensive care unit Virology law.invention Vaccination Pneumonia Respiratory failure law Pediatrics Perinatology and Child Health Epidemiology Pandemic medicine biology.protein business Intensive care medicine Neuraminidase |
Zdroj: | Journal of Pediatric Intensive Care. :217-226 |
ISSN: | 2146-4626 2146-4618 |
DOI: | 10.3233/pic-14104 |
Popis: | Seasonal influenza is a leading cause of morbidity and mortality worldwide annually while pandemic influenza, a unique entity, poses distinct challenges. The pediatric population is the primary vector for epidemics and the main focus of this article. While primary prevention with universal influenza vaccination is the best protection against significant illness, the antigenic shift and drift unique to influenza viruses leave a large population at risk even with universal vaccination. Early in an epidemic various diagnostic tests are available and discussed here. However, once an epidemic is established, testing is no longer necessary for diagnosis. Groups with particular vulnerability to serious illness include those |
Databáze: | OpenAIRE |
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