Chemotherapy and Late Course Three Dimensional Conformal Radiotherapy for Treatment of Patients with Stage III Non-small Cell Lung Cancer
Autor: | Shao-Bing Zhou, Hongxun Ye, Xin-En Huang, Jin Xiang, Yang-Chen Liu, Ying Zhao, Xiao-Xiang Yi, Fei Gao |
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Rok vydání: | 2013 |
Předmět: |
Male
Oncology Cancer Research medicine.medical_specialty Lung Neoplasms Epidemiology medicine.medical_treatment Urology Adenocarcinoma Imaging Three-Dimensional Carcinoma Non-Small-Cell Lung Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans In patient Stage (cooking) Aged Neoplasm Staging Chemotherapy business.industry Liver Neoplasms Public Health Environmental and Occupational Health Radiotherapy Dosage Chemoradiotherapy Middle Aged Prognosis Chemotherapy regimen Stage III Non-Small Cell Lung Cancer Radiation therapy Tolerability Carcinoma Squamous Cell Female Radiotherapy Conformal Three dimensional conformal radiotherapy business Follow-Up Studies |
Zdroj: | Asian Pacific Journal of Cancer Prevention. 14:2663-2665 |
ISSN: | 1513-7368 |
DOI: | 10.7314/apjcp.2013.14.4.2663 |
Popis: | Objective: To compare the efficacy and complications of chemotherapy and late course three-dimensional conformal radiotherapy (3DCRT) in treating patients with stage III non-small cell lung cancer (NSCLC). Patients and Methods: All patients were divided into two groups: to receive chemotherapy and late course 3DCRT (3DCRT group), or chemotherapy and conventional fraction radiation (control group). In the 3DCRT-group, patients were given 6~15 MV X-rays with a total dose of 40 Gy, followed by 3DCRT, 2.5 Gy~3.0 Gy per fraction, 1 fraction/ every day, total 68 Gy~70 Gy; in the control group, with conventional fraction radiation the total dose was 64~66 Gy. The chemotherapy regimen in both cases was EP (VP-16 and DDP). Results: Sixty four patients with stage III NSCLC were divided into two groups: 32 patients into 3DCRT, 32 into the control group. One and 2-year survival rates in 3DCRT and control group were 87.5%, 56.3%mad 65.6%, 34.4%, respectively (P |
Databáze: | OpenAIRE |
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