Targeting Antiretroviral Therapy: Lessons from a Longitudinal Study of Morbidity and Treatment in Relation to CD4 Count in Thailand
| Autor: | Viroj Tangcharoensathien, Steven Russell, Wanna Hanshaoworakul, Sukhum Jiamton, Yot Teerawattananon |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Longitudinal study medicine.medical_specialty Pediatrics Adolescent Relation (database) Anti-HIV Agents Health Behavior Alternative medicine HIV Infections 030209 endocrinology & metabolism 03 medical and health sciences Sex Factors 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) medicine Humans Longitudinal Studies 030212 general & internal medicine business.industry Incidence Age Factors Public Health Environmental and Occupational Health Health Services Thailand medicine.disease Antiretroviral therapy Drug Utilization CD4 Lymphocyte Count Health Care Surveys Family medicine Economic evaluation Linear Models Female Medicine Traditional business |
| Zdroj: | Asia Pacific Journal of Public Health. 18:39-48 |
| ISSN: | 1941-2479 1010-5395 |
| Popis: | The aim of the study was to quantify the incidence of illness and treatment behaviour in relation to CD4 count, age, and gender among a cohort of persons living with HIV/AIDS in Thailand. 464 participants with a CD4 count between 50 and 550 cells/mm3 were followed up for 12 months. Multiple Poisson regression was used to model the adjusted incidence rate ratio of illness and care seeking at different levels. The incidence of morbidity and treatment pattern were significantly different among participants with different CD4 count, age and gender. For example, morbidity incidence was significantly higher among participants with CD4 count of less than 200 cells/mm3, among female participants, and participants aged 35 years or over. Females made significantly higher use of hospital ambulatory care and private clinics than males and males made significantly more use of private pharmacies. The potential opportunity cost of not providing ART to these different groups can be estimated and used to inform further economic evaluation and policy decisions on whether to provide ART at all and which patient groups to prioritise. |
| Databáze: | OpenAIRE |
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