Vulval squamous cell carcinoma arising in chronic hidradenitis suppurativa
| Autor: | G. Kalu, E. M. Higgins, Peter S. Mortimer, K. A. Short |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Pathology Dermatology Disease Vulva Biopsy medicine Humans Medical history Hidradenitis suppurativa medicine.diagnostic_test Vulvar Neoplasms business.industry Glomerulonephritis Middle Aged medicine.disease Hidradenitis Suppurativa stomatognathic diseases medicine.anatomical_structure Epidermoid carcinoma Chronic Disease Carcinoma Squamous Cell Female business Nephrotic syndrome |
| Zdroj: | Clinical and experimental dermatology. 30(5) |
| ISSN: | 0307-6938 |
| Popis: | Summary We report a case of vulval squamous cell carcinoma (SCC) arising in chronic hidradenitis suppurativa (HS). The patient had a complex medical history including a 25-year-history of Crohn's disease. In addition she had recently received immunosuppressive therapy for nephrotic syndrome secondary to membranous glomerulonephritis. A painful nodule was noted on the vulva that was clinically very suspicious of SCC. An excision biopsy confirmed the diagnosis. There are few publications in the English literature citing association between HS and the development of SCC. The first report in the English literature of vulval SCC arising in chronic HS was published in 1999. We wish to draw attention to the possibility that patients with HS may develop SCC in lesional skin. A painful lump or ulcer could easily be mistaken for an inflammatory lesion and a low threshold for biopsy is warranted. We suggest constant vigilance with regard to malignant change in ano-genital HS as the diagnosis can be difficult. |
| Databáze: | OpenAIRE |
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