Acupuncture Stimulation at Sanyinjiao: Effect on the Sodium Pertechnetate Bioavailability in Rats
| Autor: | Lavínia C. Brito, Marcela C. Almeida, Mario Bernardo-Filho, Cristiano Viana Manoel, Daisy L.M. França, Deise Elisabete de Souza, Raphael Sancho Sisley de Souza, Vasco Senna-Fernandes |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Biological Availability Stimulation Sodium pertechnetate chemistry.chemical_compound Internal medicine Intestine Small Acupuncture Animals Medicine Rats Wistar Pancreas Sodium Pertechnetate Tc 99m business.industry General Medicine Small intestine Rats Bioavailability medicine.anatomical_structure Endocrinology Liver Complementary and alternative medicine chemistry Acupuncture point Reflex Radiopharmaceuticals business Acupuncture Points Technetium-99m Injections Intraperitoneal Spleen |
| Zdroj: | The American Journal of Chinese Medicine. 35:977-986 |
| ISSN: | 1793-6853 0192-415X |
| Popis: | In clinical acupuncture, when acupuncture points are stimulated, several types of reflex responses can be evoked. Consequently, different categories of physiological responses are induced, which include changes in the activities of internal organs and tissues. The acupuncture point Sanyinjiao (SP6) has been used successfully to treat different human gastrointestinal conditions. The aim of this work was to investigate the effects of end-organ response induced by acupuncture point SP6 on the bioavailability of the radiopharmaceutical sodium pertechnetate ( Na 99 m TcO 4) in Wistar rats. Healthy rats were allocated into 2 groups, control-CG and treated-TG. TG was bilaterally stimulated at acupuncture point SP6 with stainless steel needles. Ocular plexus administration of Na 99 m TcO 4 (3.7MBq) was carried out 10 min after every needle insertion in all animals. Ten minutes later, the animals were killed, the organs were isolated, the radioactivity was determined in a well gamma counter, and the percentage of injected dose per gram of tissue (%ID/g) was determined for each organ. The %ID/g was significantly altered ( p < 0.05) in the small intestine of TG (0.56 ± 0.09) when compared to CG (0.82 ± 0.18). These results may suggest that this stimulation might induce physiological responses capable of altering the bioavailability of the radiopharmaceutical sodium pertechnetate. These findings aid in providing a better understanding of acupuncture and its effects on various organs and tissues. |
| Databáze: | OpenAIRE |
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