Efficacy of the spray-drying treatment to inactivate the bovine leukemia virus in bovine colostrum
| Autor: | Natalia Gabriela Porta, Mariana Sowul, Darío Amilcar Malacari, Gerónimo Gutiérrez, K. Trono, Osvaldo Zabal, Marina Lomonaco, Irene Alvarez |
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| Rok vydání: | 2019 |
| Předmět: |
Food Handling
viruses animal diseases Biology Antibodies Viral Virus 03 medical and health sciences fluids and secretions Pregnancy Genetics Leukemia Virus Bovine Animals 030304 developmental biology Infectivity 0303 health sciences Bovine leukemia virus Transmission (medicine) Inoculation Colostrum 0402 animal and dairy science food and beverages 04 agricultural and veterinary sciences Provirus Enzootic Bovine Leukosis biology.organism_classification 040201 dairy & animal science Virology Freeze Drying Milk biology.protein Food Microbiology Animal Science and Zoology Cattle Female Antibody Food Science |
| Zdroj: | Journal of dairy science. 103(7) |
| ISSN: | 1525-3198 |
| Popis: | Previous studies have shown the presence of bovine leukemia virus (BLV) in colostrum and milk of naturally infected cows. The relationship between virus or provirus and specific antibodies in these secretions is particular to each infected cow and will probably determine whether the consumption of colostrum or milk from these naturally infected dams provides an infective or a protective effect in recipient calves. Our recent findings suggest that this issue is a key point in BLV transmission in very young calves. Based on this, the aim of the present study was to determine the effect of the spray-drying treatment of colostrum on BLV infectivity. The treatment was done on scale-down conditions, using fresh colostrum from BLV-negative cows spiked with infective BLV. Residual infectivity was tested in susceptible lambs. Lambs inoculated with colostrum spiked with BLV-infected cells or cell-free BLV showed evidence of infection 60 d after inoculation, whereas none of the lambs inoculated with spray-dried colostrum showed evidence of infection 60 d after inoculation. These results provide direct evidence that the experimental spray-drying process used in this study was effective in inactivating infectious BLV in colostrum. These findings suggest that the risk for BLV transmission could be reduced if milk and colostrum were treated by spray-drying prior to consumption in dairy facilities. The effect of spray-drying on the functional properties and stability of the antibodies present in colostrum under long-term storage should be further investigated. |
| Databáze: | OpenAIRE |
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