Reconfigurable hardware-software codesign methodology for protein identification
| Autor: | Vasundhra Bhandari, Sandeep Thallada, Venkata Krishna Gande, Saqib Khursheed, Ganesh R. Naik, Abhinay RamRaj Deevi, Venkateshwarlu Y. Gudur, Amit Acharyya, Paresh Sharma |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Flexibility (engineering) Engineering Theoretical computer science Time Factors business.industry Computers Reconfigurability Proteins String searching algorithm Reconfigurable computing 03 medical and health sciences ComputingMethodologies_PATTERNRECOGNITION 030104 developmental biology Software Computer architecture Humans Algorithm design UniProt business Field-programmable gate array Databases Protein |
| Zdroj: | EMBC |
| ISSN: | 2694-0604 |
| Popis: | © 2016 IEEE. In this paper we propose an on-the-fly reconfigurable hardware-software codesign based reconfigurable solution for real-time protein identification. Reconfigurable string matching is performed in the disciplines of protein identification and biomarkers discovery. With the generation of plethora of sequenced data and number of biomarkers for several diseases, it is becoming necessary to have an accelerated processing and on-the-fly reconfigurable system design methodology to bring flexibility to its usage in the medical science community without the need of changing the entire hardware every time with the advent of new biomarker or protein. The proteome database of human at UniProtKB (Proteome ID up000005640) comprising of 42132 canonical and isoform proteins with variable database-size are used for testing the proposed design and the performance of the proposed system has been found to compare favorably with the state-of-the-art approaches with the additional advantage of real-time reconfigurability. |
| Databáze: | OpenAIRE |
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