Rocuronium is associated with an increased risk of reintubation in patients with soft tissue infections
| Autor: | Samuel M. Galvagno, Bianca M. Conti, Karla M. Greco, Cynthia J. Bucci |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Risk Factors medicine Intubation Intratracheal Odds Ratio Humans Androstanols Rocuronium Aged Retrospective Studies business.industry Soft Tissue Infections Trauma center Case-control study Soft tissue Retrospective cohort study Odds ratio Middle Aged Neuromuscular monitoring Anesthesiology and Pain Medicine 030228 respiratory system Anesthesia Case-Control Studies Anesthesia Recovery Period Airway Extubation Neuromuscular Blockade Female business Body mass index medicine.drug Neuromuscular Nondepolarizing Agents |
| Zdroj: | Journal of clinical anesthesia. 34 |
| ISSN: | 1873-4529 |
| Popis: | Study Objective To determine risk factors associated with reintubations in adult patients with soft tissue infections. Design A retrospective case-control design. Setting Operating room and postoperative recovery area. Patients There were 39 patients who presented for surgical intervention of their soft tissue infection and 222 controls having general surgery who were matched for age, sex, and body mass index. All patients were older than the age of 18 years and mostly American Society of Anesthesiologists physical status of III to IV and presented to our level 1 trauma center. Interventions Reintubation within 2 hours after planned extubation. Measurements The following data were collected: reintubation rates, train of four ratio, reversal agents, age, sex, creatinine, smoking history, transfusion requirements, Sequential Organ Failure Assessment score, hemoglobin, and lactate. Main Results The use of rocuronium was independently associated with increased odds of reintubation. Patients with a higher train of four ratio were more likely to be reintubated and less likely to be reversed as compared to those with a lower train of four ratio. Conclusions Soft tissue patients who have received rocuronium are at increased risk for reintubation, particularly those with renal failure. In addition, this article supports the use of neuromuscular blockade reversals, even in patients with a strong train of four ratio. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect