Prognostic effect of implementation of the mass low-dose computed tomography lung cancer screening program: a hospital-based cohort study
| Autor: | En Kuei Tang, Chi Shen Chen, Yun Ju Wu, Yi Luan Huang, Fu Zong Wu, Yun Pei Lin, Ming Ting Wu |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Lung Neoplasms Epidemiology Taiwan 03 medical and health sciences 0302 clinical medicine Humans Medicine Registries 030212 general & internal medicine Mortality Lung cancer Survival rate Early Detection of Cancer Aged Retrospective Studies business.industry Mortality rate Health Plan Implementation Public Health Environmental and Occupational Health Retrospective cohort study respiratory system Prognosis medicine.disease Hospitals respiratory tract diseases Cancer registry Survival Rate Oncology 030220 oncology & carcinogenesis Cohort Female Radiology Tomography X-Ray Computed business Lung cancer screening Follow-Up Studies Cohort study |
| Zdroj: | European Journal of Cancer Prevention. 29:445-451 |
| ISSN: | 0959-8278 |
| DOI: | 10.1097/cej.0000000000000569 |
| Popis: | Low-dose computed tomography lung cancer screening aims to detect early-stage lung cancers in order to decrease the incidence of advanced-stage lung cancers and to reduce lung cancer mortality. We analyzed the time trends of lung cancer stage distribution and mortality rates after the gradual implementation of the low-dose computed tomography lung cancer screening in a hospital-based cohort. Using the hospital-based cancer registry data on lung cancer number and death from 2007 to 2014, we aim to evaluate the trends in stage distribution and mortality rate after the gradual implementation of low-dose computed tomography lung cancer screening program over recent years. From 2007 to 2014, overall 2542 cases of lung cancers were diagnosed according to hospital-based cancer registry. For the 1-year mortality rate, the mortality rate decreased gradually from 48.16 to 37.04% between 2007 and 2014. For the 5-year mortality rate, the mortality rate decreased gradually from 88.49 to 69.44% between 2007 and 2014. There was a gradual decrease in stage IV lung cancer with the corresponding sharp increase in stage I early lung cancer after following the implementation of the large volume of the low-dose computed tomography examination between the years 2011 and 2014. In conclusion, these results suggest that the gradual implementation of low-dose computed tomography lung screening program could lead to a remarkable decrease in lung cancer mortality and a remarkable stage shift in the trend over time in this hospital-based cohort. |
| Databáze: | OpenAIRE |
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