Hypoglycaemia associated with gastrointestinal and extragastrointestinal stromal tumour in two dogs
| Autor: | Clara Ballber, Sionagh Smith, Spela Bavcar, Joanna Lodzinska |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty Stromal cell 040301 veterinary sciences Gastrointestinal smooth muscle EGIST 0403 veterinary science symbols.namesake Dogs Medicine neoplasms Computed tomography Ultrasonography Tumour excision Gastrointestinal tract General Veterinary GiST business.industry Mesenchymal stem cell 0402 animal and dairy science 04 agricultural and veterinary sciences 040201 dairy & animal science digestive system diseases Interstitial cell of Cajal symbols Immunohistochemistry business GIST |
| Zdroj: | Lodzinska, J, Ballber, C, Smith, S & Bavcar, S 2019, ' Hypoglycaemia associated with gastrointestinal and extragastrointestinal stromal tumour in two dogs ', Vet Record Case Reports, vol. 7, no. 4 . https://doi.org/10.1136/vetreccr-2018-000784 |
| Popis: | Gastrointestinal stromal tumours (GISTs) are uncommon mesenchymaltumours that originate from the interstitial cells of Cajal (ICC). As thesetumours are difficult to distinguish from gastrointestinal smooth muscletumours using standard histological techniques, their true prevalencemay be underestimated. Metabolic and systemic consequences of GISTsare not well described in any species. More rarely, neoplasms withhistological and immunohistochemical features similar to GISTs mayoccur outside the gastrointestinal tract, so-called Extra-gastrointestinalStromal Tumours (EGIST). EGISTs have never been described in theveterinary literature. In this article we present and describe clinicalfindings, management and treatment of two dogs with clinicalhypoglycaemia induced by histologically confirmed GIST and EGIST.Hypoglycaemia resolved immediately and long-term after tumourexcision. To the authors’ knowledge this is the first report ofhypoglycaemia associated with a canine GIST and the first case report ofan EGIST in the dog. |
| Databáze: | OpenAIRE |
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