Longitudinal study of serum thyroid hormone levels during normal pregnancy
| Autor: | G. Atkinson, Peter O'Leary, K.-J. Mileham, Ian James, Peter Boyne |
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| Rok vydání: | 1992 |
| Předmět: |
endocrine system
medicine.medical_specialty Thyroid Hormones endocrine system diseases Reference range Thyroid function tests Thyroxine-binding globulin Pregnancy Internal medicine medicine Humans Longitudinal Studies Prospective Studies Triiodothyronine biology medicine.diagnostic_test business.industry Thyroid Obstetrics and Gynecology General Medicine medicine.disease medicine.anatomical_structure Endocrinology biology.protein Female Thyroid function business Hormone |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 38(3) |
| ISSN: | 0020-7292 |
| Popis: | We undertook a prospective longitudinal study of thyroid function in 60 normal pregnant women and measured serum concentrations of T4, triiodothyronine (T3), T-uptake, thyroxine binding globulin (TBG), free thyroxine index (FTI), free T4, albumin and thyrotropin (TSH). From these data we established reference ranges for each of these analytes for each trimester and examined the inter-relationships between laboratory measurements of thyroid function tests. We observed significant increases in serum concentrations of thyrotropin and decreases in free T4, assays commonly used as first line investigations of thyroid activity during pregnancy. However, the 95th centile intervals for both analytes remained within the reference range for nonpregnant women. |
| Databáze: | OpenAIRE |
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