Subgingival Microflora Associated With Nifedipine-Induced Gingival Overgrowth
| Autor: | Mela Nakou, Alkyoni Andronikaki, Joanna J. Kamma, Fotis J. Mitsis |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Nifedipine Bacteroidaceae Dental Plaque Gingiva Campylobacter concisus Gingival Pocket Gram-Positive Bacteria Eubacterium alactolyticum Microbiology Propionibacterium acnes Fusobacterium mortiferum stomatognathic system Gram-Negative Bacteria Bacteroides Humans Medicine Aged Fusobacterium nucleatum biology Eubacterium Gingival Overgrowth business.industry Dental Plaque Index Capnocytophaga ochracea Age Factors Campylobacter Fusobacterium Middle Aged Calcium Channel Blockers biology.organism_classification Capnocytophaga gingivalis Gingivitis stomatognathic diseases Logistic Models Periodontics Female Periodontal Index Gingival Hemorrhage business Capnocytophaga Forecasting |
| Zdroj: | Journal of Periodontology. 69:664-669 |
| ISSN: | 1943-3670 0022-3492 |
| DOI: | 10.1902/jop.1998.69.6.664 |
| Popis: | The purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (GO). Age was inversely associated with the GO. Plaque index and bleeding index showed a significant association with GO, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of GO. The gingival inflammation as expressed in the logistic regression model by the interaction term color x tone was found to be significantly associated with the GO. Statistically significant differences between the groups of comparable probing depth and different degrees of GO were detected for Propionibacterium acnes, Capnocytophaga gingivalis, Capnocytophaga ochracea, Capnocytophaga sputigena, Bacteroides gracilis, Fusobacterium mortiferum, Fusobacterium nucleatum, Fusobacterium varium and Selenomonas sputigena in deep and enlarged lesions. Significantly more frequently isolated were the bacterial species Eubacterium alactolyticum, Campylobacter concisus, C. gingivalis, C. ochracea, C. sputigena, F. mortiferum, F. nucleatum, and F. varium from the more enlarged lesions (GO >3). |
| Databáze: | OpenAIRE |
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