GH, ACTH, TSH, LH, and FSH Reserve in Prepubertal Girls with Congenital Adrenal Hyperplasia
| Autor: | Silvana Salardi, Paola Tassoni, Laura Mazzanti, Filippo Bernardi, Piero Pirazzoli, Emanuele Cacciari, Patrizia Vianelli, Alessandro Cicognani, Franco Zappulla |
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| Rok vydání: | 1976 |
| Předmět: |
endocrine system
Pituitary gland medicine.medical_specialty Adrenocortical Hyperfunction endocrine system diseases Insulin induced hypoglycemia Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Thyrotropin Gonadotropin-releasing hormone Hypoglycemia Biochemistry Endocrinology Adrenocorticotropic Hormone Internal medicine medicine Humans Congenital adrenal hyperplasia Normal range business.industry Insulin Puberty Biochemistry (medical) Age Factors Luteinizing Hormone medicine.disease Cortisone Pituitary Hormones medicine.anatomical_structure Growth Hormone Female Follicle Stimulating Hormone business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 43:1146-1152 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-43-5-1146 |
| Popis: | The pituitary reserve of GH, ACTH, TSH, LH, and FSH was determined in seven prepubertal birls suffering from congenital adrenal hyperplasia due to 21-hydroxylation defect and under treatment with cortisone acetate. GH and ACTH were studied during the insulin induced hypoglycemia test. The LH, FSH, and TSH reserved were assayed by means of the LH-RH and TRH tests. GH behavior proved to be similar to that found in normal subjects, whereas basal and/or after stimulus ACTH turned out to be higher than the upper limits of the normal range in five out of six girls. The mean basal value and the mean LH peak were not significantly higher than those found in normal prepubertal girls; the mean basal value and the mean FSH peak were lower than the mean of the control group. The difference is significant (P less than 0.05) only between the peak values. The mean basal TSH in the patients is significantly higher (P less than 0.01) than the mean value of the control group. The maximum TSH after TRH is not significantly different from the mean value fo the control group. |
| Databáze: | OpenAIRE |
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