| Popis: |
Figure S2. EP4 is not overexpressed in other CD4+ T cell subsets. (a) Ex vivo analysis of human CD4+ T cell subsets and (b) EP4 expression (HC n ≥ 6, AS n = 17, RA n ≥ 9, PsA n ≥ 6; *p = 0.05, p value calculated using Mann-Whitney test). (c) Cytokine expression and (d) EP4 expression in induced CD4+ T cell subsets after 4 days of in vitro cell culture. Th0, Th1, Th2, Th9, and iTreg cells were induced from naïve CD4+ CD45RA+ CD45RO− T cells (AS n = 8, RA n ≥ 4, PsA n = 6). (e) Relative expression of PGE2 receptor genes was assessed by RT-PCR (n = 3, p value calculated using Kruskal-Wallis test). Data are shown as mean ± SEM. (PDF 105 kb) |
