Polyhydroxylated Spirostanol Saponins from the Tubers of Dioscorea polygonoides
| Autor: | Kazuki Watanabe, Oscar Marino Mosquera Martínez, Yoshihiro Mimaki, Jaime Niño Osorio, Yaned M. Correa Navarro, Hiroshi Sakagami |
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| Rok vydání: | 2005 |
| Předmět: |
Tubercle
Stereochemistry Dioscoreaceae Saponin Pharmaceutical Science Analytical Chemistry Enzymatic hydrolysis Drug Discovery Spirostans Nuclear Magnetic Resonance Biomolecular Pharmacology chemistry.chemical_classification Plants Medicinal Molecular Structure biology Traditional medicine Dioscorea Organic Chemistry Glycoside Stereoisomerism Saponins biology.organism_classification Complementary and alternative medicine chemistry Dioscorea polygonoides Molecular Medicine Acid hydrolysis |
| Zdroj: | Journal of Natural Products. 68:1116-1120 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np0580356 |
| Popis: | Three new polyhydroxylated spirostanol saponins (1-3) were isolated from the tubers of Dioscorea polygonoides. The structures of these new compounds were determined on the basis of extensive spectroscopic analysis and the results of acid or enzymatic hydrolysis as (23S,24R,25S)-23,24-dihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1--2)-beta-D-glucopyranoside (1), (23S,25R)-12alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1--2)-beta-D-glucopyranoside (2), and (23S,25R)-14alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1--2)-beta-D-glucopyranoside (3), respectively. |
| Databáze: | OpenAIRE |
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