Photothermal and adsorption effects of silver selenide nanoparticles modified by different surfactants in nursing care of cancer patients
| Autor: | Yue Wang, Chen Wang, Guiqin Zhang, Feng Gao, Xiaoxu Zhang, Xingju Yang, Wenli Xu, Changxiu Qiao, Lixia Sun |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
synthesis Nanoparticle Nanotechnology 02 engineering and technology 212 Surface and interfaces 010402 general chemistry 01 natural sciences surfactants chemistry.chemical_compound Nursing care photothermal Adsorption 301 Chemical syntheses / processing Selenide General Materials Science characterization Materials of engineering and construction. Mechanics of materials Bio-Inspired and Biomedical Materials Light response 503 TEM Photothermal therapy STEM 021001 nanoscience & nanotechnology 0104 chemical sciences chemistry SEM TA401-492 Surface modification silver selenide 0210 nano-technology TP248.13-248.65 Research Article Biotechnology |
| Zdroj: | Science and Technology of Advanced Materials, Vol 21, Iss 1, Pp 584-592 (2020) Science and Technology of Advanced Materials article-version (VoR) Version of Record |
| ISSN: | 1878-5514 1468-6996 |
| Popis: | Silver selenide nanoparticles have advantages of low cytotoxicity, desirable near-infrared light response characteristics, and easy surface modification, which attract increasing attention in chemo-photothermal therapy and nursing care of cancer patients. In this contribution, we synthesized Ag2Se nanoparticles modified by the surfactant of cetyltrimethylammonium bromide (CTAB) using a ligand exchange strategy. Their microstructure and composition were characterized by transmission electron microscopy, X-ray diffraction, X-ray Photo-electronic Spectroscopy, and Fourier transform infrared spectroscopy. The CTAB modified Ag2Se nanoparticles exhibited a uniform diameter distribution centered at ~12 nm. In order to investigate the photothermal and adsorption effects of CTAB-Ag2Se nanocomposites, we also prepared sodium dodecyl benzene sulfonate (SDBS) modified Ag2Se nanoparticles to make a comparison. The CTAB-Ag2Se nanoparticles showed high photothermal properties, a photothermal conversion efficiency of 20.1% and a high drug adsorption performance of 48.2 μg/mg. Importantly, the CTAB-Ag2Se-DOX presented an MCF-7 cell activity of only 27.3% under near-infrared radiation. The results revealed that the surface-modified Ag2Se nanoparticles with CTAB had stronger antitumor ability. Graphical Abstract |
| Databáze: | OpenAIRE |
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