In vitro adherence property of cytolethal distending toxin (CLDT) producing EPEC strains and effect of the toxin on rabbit intestine

Autor: A. Varghese, Saeid Bouzari, B. R. Vatsala
Rok vydání: 1992
Předmět:
Zdroj: Microbial pathogenesis. 12(2)
ISSN: 0882-4010
Popis: Sixteen cytolethal distending toxin-producing enteropathogenic Esherichia coli (CLDT+ EPEC) strains of six different serogroups were included in this study. The strains showed varying adherence patterns on HEp-2 cells, i.e. six strains showed localized adherence (LA), five strains exhibited diffuse adherence (DA) and five strains were non-adherent. Histological study of rabbit ileal segments showed that live cultures of CLDT+ EPEC did not cause lesions characteristic of attachment and effacement (AE) and the toxin effect resembled that of classical LT or CT.
Databáze: OpenAIRE