Mammary core clock gene expression is impacted by photoperiod exposure during the dry period in goats
| Autor: | Mugagga Kalyesubula, Avi Shamay, Karen Plaut, Yosi Wein, Enav Bar-Shira, Sameer J. Mabjeesh, C. Sabastian, Naama Reicher, Theresa Casey |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
endocrine system Photoperiod Period (gene) Circadian clock Biology 03 medical and health sciences Animal science Lactation circadian clock medicine mammary reproductive and urinary physiology photoperiodism dry period lcsh:Veterinary medicine General Veterinary goat food and beverages Prolactin CLOCK ARNTL 030104 developmental biology medicine.anatomical_structure lcsh:SF600-1100 Animal Science and Zoology hormones hormone substitutes and hormone antagonists PER1 |
| Zdroj: | Journal of Applied Animal Research, Vol 46, Iss 1, Pp 1214-1219 (2018) |
| ISSN: | 0974-1844 0971-2119 |
| Popis: | Short-day photoperiod (SDPP) during the dry period increases milk production compared to long-day photoperiod (LDPP) in goats. Photoperiod information is sent to the master clock in the suprachiasmatic nuclei (SCN), which send temporal information to peripheral clocks located in every tissue of the body. We hypothesized photoperiod effects on milk production are mediated in part by changes in mammary clocks. Our objective was to determine the effect of photoperiod manipulation during the dry period in goats on core clock genes expression in mammary gland. Multiparous goats (n = 6) were blocked at dry off into two treatments: LDPP and SDPP. Serial mammary biopsies were taken over a 24 h period during three weeks prepartum. Total RNA was isolated, and q-PCR analysis of the core clock genes CLOCK, ARNTL, PER1, CRY1, and CRY2 found exposure to LDPP significantly increased ARNTL (P |
| Databáze: | OpenAIRE |
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