4D Flow CMR in Assessment of Valve-Related Ascending Aortic Disease
| Autor: | Karen G. Ordovas, Stephen E. S. Crook, Thomas A. Hope, Michael D. Hope, Thomas H. Urbania, Marc T. Alley, Charles B. Higgins |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Heart Defects Congenital Male Aortic valve medicine.medical_specialty bicuspid aortic valve Adolescent eccentric jets Hemodynamics Aorta Thoracic Pilot Projects Risk Assessment cardiac magnetic resonance valves Young Adult Bicuspid aortic valve Aneurysm Risk Factors Internal medicine medicine.artery medicine Humans Eccentric Radiology Nuclear Medicine and imaging Aorta medicine.diagnostic_test business.industry Magnetic resonance imaging Blood flow medicine.disease Magnetic Resonance Imaging Aortic Aneurysm 4D Flow aorta medicine.anatomical_structure Radiology Nuclear Medicine and imaging Aortic Valve cardiovascular system Cardiology Female Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | JACC: Cardiovascular Imaging. 4:781-787 |
| ISSN: | 1936-878X |
| DOI: | 10.1016/j.jcmg.2011.05.004 |
| Popis: | Blood flow imaging with 3-dimensional time-resolved, phase-contrast cardiac magnetic resonance (4-dimensional [4D] Flow) is an innovative and visually appealing method for studying cardiovascular disease that allows quantification of important secondary vascular parameters including wall shear stress. The hypothesis of this pilot study is that 4D Flow will become a powerful tool for characterizing the relationship of aortic valve–related flow dynamics, especially with bicuspid aortic valve (BAV), and progression of ascending aortic (AsAo) dilation. We identified 46 patients previously studied with 4D Flow: tricuspid aortic valve patients without valvular disease (n = 20), and BAV patients with either normal flow (n = 7) or eccentric systolic jets resulting in abnormal right-handed helical AsAo flow (n = 19). The subgroup of patients with BAV and eccentric systolic AsAo blood flow was found to have significantly and asymmetrically elevated wall shear stress. This increased hemodynamic burden may place them at risk for AsAo aneurysm. |
| Databáze: | OpenAIRE |
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