Quantitative Measurement of Protein Using Metal Mesh Device
| Autor: | Yoshiko Miura, Takashi Kondo, Hirokazu Seto, Seiji Kamba |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
010302 applied physics
Chemistry Analytical chemistry Proteins Biosensing Techniques 02 engineering and technology 021001 nanoscience & nanotechnology Electromagnetic field computation 01 natural sciences Protein detection Analytical Chemistry Terahertz spectroscopy and technology Electromagnetic Fields Adsorption Metals 0103 physical sciences Metal mesh Equivalent circuit Sensitivity (control systems) 0210 nano-technology Protein adsorption |
| Zdroj: | Analytical Sciences. 33:1033-1039 |
| ISSN: | 1348-2246 0910-6340 |
| Popis: | Biosensing of protein adsorption with metal mesh device (MMD) was investigated by computational calculations and experiments. Electromagnetic field computation was carried out with a single unit cell of MMD. Equivalent circuit model of MMD on the single unit cell was assumed, and the biosensing with MMD was analyzed in detail by computational calculation and experimental measurements. The dip frequency of MMD was shifted by adsorption of protein on MMD. The shift of dip frequency of MMD was proportional to the amount of protein adsorption. The sensitivity of MMD biosensing was dependent on the microstructure of MMD, and proportional to the square of the dip frequency. The refinement of MMD structure can improve the sensitivity of protein detection. |
| Databáze: | OpenAIRE |
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