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Cheremisina V. F. The role of connective tissue metabolic processes in the development of pathological processes at inflammation of different intensity in parodontium. Journal of Education, Health and Sport. 2018;8(8):1250-1254. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1468873 http://ojs.ukw.edu.pl/index.php/johs/article/view/6214 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author(s) 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.08.2018. Revised: 14.08.2018. Accepted: 31.08.2018. THE ROLE OF CONNECTIVE TISSUE METABOLIC PROCESSES IN THE DEVELOPMENT OF PATHOLOGICAL PROCESSES AT INFLAMMATION OF DIFFERENT INTENSITY IN PARODONTIUM V. F. Cheremisina Kharkov National Pharmaceutical University, Ukraine; e-mail: cheremishav@gmail.com Abstract The objective. To study metabolic processes in connective tissue (CT) at different intensity of inflammation in parodontium. Materials and methods. The research is conducted on the sample of oxyproline, which is one of the indicators in the study of metabolic processes in the CT. This amino-acid presents in the blood in the free state, reflects the processes of collagen degradation in the form of protein-binding oxyproline and has no unambiguous interpretation. Results. At low intensity of the imflammation in the periodontium (stomatitis and alveolitis), the synthesis and collagen degradation are in relative equilibrium, and an increase in its intensity (gingivitis and especially periodontitis) leads to its violation. Conclusions. It has been established that the CT plays an important role in the development of pathological processes in periodontal tissues. The concentration of free and peptide-linked oxyproline in serum is higher in the groups of patients with more severe periodontal inflammation (periodontitis and gingivitis). Key words: oxyproline, connective tissue, periodontal tissue. |
