Menière's disease patients improve specific posturographic parameters following diagnostic intratympanic injection
Autor: | Maria A. Mariggiò, Danilo Bondi, Armando Tartaro, Giampiero Neri, Andrea Scordella, Fiorella Cazzato, Letizia Neri, Niccolò Pini |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty Tympanic Membrane Contrast Media Gadolinium 03 medical and health sciences 0302 clinical medicine Pressure medicine Humans Endolymphatic Hydrops Inner ear Endolymphatic hydrops 030223 otorhinolaryngology Postural Balance Meniere Disease Aged Retrospective Studies Balance (ability) Vestibular system Injection Intratympanic medicine.diagnostic_test business.industry Posturography Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Otorhinolaryngology Ear Inner 030220 oncology & carcinogenesis Female Vestibule Labyrinth business Nuclear medicine Meniere's disease |
Zdroj: | American Journal of Otolaryngology. 41:102468 |
ISSN: | 0196-0709 |
Popis: | Purpose Evaluation of specific computerized posturographic parameters in patients with Meniere's disease (MD) following the intratympanic injection of gadolinium, a contrast agent, used in radiological diagnosing. Materials and methods We have observed 12 adult patients with unilateral Meniere's Disease subjected to inner ear magnetic resonance imaging (MRI) examination after intratympanic gadolinium injection (ITG). The diagnoses have been performed according to the guidelines of the American Academy of otolaryngology. Before and after 24 h the ITG, all patients were subjected to the clinical evaluation and computerized posturography (CP), in 4 conditions depending on open/closed eyes and with/without foam cushion under feet. Results After ITG, in the affected ear the MRI confirmed the endolymphatic hydrops revealing a thin or even disappeared perilymphatic space. The statokinesigram showed improvement of stability only with closed eyes on a foam cushion. The CP performed 24 h after the contrast intratympanic injection showed a significant reduction of Path Length and Confidence Ellipse Area, due to an improvement of vestibular function on static balance. This improvement could be directly dependent to intratympanic pressure modification mediated by volume of contrast liquid, by “columella effect”. Conclusions This study demonstrates the absence of vestibular damage in patients undergoing intratympanic gadolinium infiltration and confirms the relationship between intratympanic pressure and vestibular stability modifications providing positive evidences for an applicative use of CP as a functional assessment to better address diagnosis and follow-up in MD patients treated with intratympanic injections. |
Databáze: | OpenAIRE |
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