Exhaled nitric oxide and spirometry in respiratory health surveillance
| Autor: | B. Hannhart, Denis Zmirou-Navier, Dan B. Teculescu, Abraham Bohadana, H. Ghezzo |
|---|---|
| Přispěvatelé: | Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Ecole de Santé Publique [Nancy], Faculté de Médecine [Nancy], Université de Lorraine (UL)-Université de Lorraine (UL) |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Male
Vital capacity health surveillance MESH: Asthma Food Handling Vital Capacity spirometry Hair Preparations MESH: Occupational Exposure Atopy 0302 clinical medicine Forced Expiratory Volume Surveys and Questionnaires 030212 general & internal medicine medicine.diagnostic_test Respiratory disease 3. Good health Occupational Diseases Breath Tests Population Surveillance Female France FENO MESH: Food Handling Airway inflammation apprentice bakers Spirometry MESH: Occupational Diseases medicine.medical_specialty Adolescent Air Pollutants Occupational MESH: Forced Expiratory Volume Nitric Oxide MESH: Air Pollutants Occupational MESH: Population Surveillance 03 medical and health sciences FEV1/FVC ratio Internal medicine Occupational Exposure medicine Humans Asthma MESH: Adolescent MESH: Humans business.industry MESH: Questionnaires Public Health Environmental and Occupational Health MESH: Hair Preparations Airway obstruction MESH: Vital Capacity medicine.disease MESH: Male respiratory tract diseases MESH: France MESH: Breath Tests 030228 respiratory system MESH: Nitric Oxide Exhaled nitric oxide occupational health Physical therapy [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie MESH: Spirometry business apprentice hairdressers MESH: Female |
| Zdroj: | Occupational Medicine Occupational Medicine, Oxford University Press (OUP), 2011, 61 (2), pp.108-14. ⟨10.1093/occmed/kqq184⟩ |
| ISSN: | 0962-7480 1471-8405 |
| DOI: | 10.1093/occmed/kqq184⟩ |
| Popis: | International audience; BACKGROUND: Exposure to pollutants in bakeries and hairdressing salons can cause airway syndromes varying from bronchial irritation to asthma. Workplace respiratory health surveillance aims to identify possible cases requiring further investigation. AIMS: To compare the performance of fractional exhaled nitric oxide (FE(NO)) and spirometry for health surveillance of apprentice bakers (ABs) and apprentice hairdressers (AHDs). Determinants of FE(NO) were also identified. METHODS: Symptoms and physician-diagnosed asthma were evaluated by questionnaire. FE(NO) was measured and spirometry was carried out. Subjects with elevated FE(NO) (FE(NO) > upper limit normal), airway obstruction [forced expiratory volume in 1 s (FEV(1))/forced vital capacity (FVC) < 95th percentile] and atopy (history of allergies) were identified. RESULTS: A total of 126 apprentices (59 ABs and 67 AHDs) participated. Twenty-nine (23%) apprentices had abnormal tests: 4 had associated high FE(NO) and airway obstruction, while 25 had either high FE(NO) (n = 15) or airway obstruction (n = 10) alone. Compared with ABs (n = 16), AHDs (n = 13) had more asthma (38 versus 0%; P < 0.05) and atopy (62 versus 6%; P < 0.05). There was no difference in symptoms, smoking FE(NO) or airways obstruction. Among 97 subjects with normal tests, no differences existed between ABs (n = 53) and AHDs (n = 44). Average FE(NO) was increased in atopic non-smokers compared with atopic smokers and non-atopic subjects (P < 0.05). Smoking, a history of allergies, FEV(1)/FVC % observed and respiratory symptoms were the main determinants of FE(NO). CONCLUSIONS: FE(NO) and spirometry were not overlapping dimensions in ABs and hairdressers, each test contributing unique information on the physiological status of the respiratory system. FE(NO) may provide added information on airway inflammation not provided by spirometry. |
| Databáze: | OpenAIRE |
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