An analysis of antidepressant prescribing trends in England 2015–2019
Autor: | Sarah J. Bailey, Anita McGrogan, Hasnain Lalji |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Population General Practice Antidepressant Disease NHS National Health Service Citalopram SNRI serotonin and noradrenaline reuptake inhibitor SDG 3 - Good Health and Well-being medicine IMD index of multiple deprivation Medical prescription education RZ400-408 SSRI selective serotonin reuptake inhibitor Depression (differential diagnoses) COVID-19 coronavirus disease 2019 Sertraline education.field_of_study business.industry Depression Mental health NHSBSA NHS Business Services Authority CCG Clinical Commissioning Group Emergency medicine business Cardiovascular prescribing Mental healing Research Paper medicine.drug |
Zdroj: | Journal of Affective Disorders Reports, Vol 6, Iss, Pp 100205-(2021) Lalji, H M, McGrogan, A & Bailey, S 2021, ' An analysis of antidepressant prescribing trends in England 2015-2019 ', Journal of Affective Disorders Reports, vol. 6, 100205 . https://doi.org/10.1016/j.jadr.2021.100205 Journal of Affective Disorders Reports |
ISSN: | 2666-9153 |
DOI: | 10.1016/j.jadr.2021.100205 |
Popis: | Background: Growing concerns about the impact of coronavirus disease 2019 (COVID-19) will likely lead to increased mental health diagnoses and treatment. To provide a pre-COVID-19 baseline, we have examined antidepressant prescribing trends for 5 years preceding COVID-19. Methods: A retrospective analysis of anonymised data on medicines prescribed by GPs in England from the Open-Prescribing Database (January 2015 to December 2019) identified the 10 most prescribed antidepressant and, for comparison, cardiovascular medicines. Results: Prescription items for the 10 most prescribed antidepressants rose 25% from 58 million (2015) to 72 million (2019). Citalopram was the most prescribed antidepressant; prescriptions for sertraline rose fastest at 2 million items year on year. Over the same period, costs for antidepressant prescribing fell 27.8%. Across all Clinical Commissioning Groups (CCGs) in England, antidepressant prescribing levels, adjusted for population were positively correlated with the index of multiple deprivation (IMD) score. In comparison, prescribing for the top 10 most prescribed cardiovascular medicines increased by 2.75% from 207 million (2015) to 213 million (2019) items. Limitations: Anonymised data in the Open-Prescribing Database means no patient diagnoses or treatment plans are linked to this data. Conclusion: Antidepressant prescribing, particularly sertraline, is increasing. Prescribing is higher in more deprived regions, but costs are falling to |
Databáze: | OpenAIRE |
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