Co-suppression of β-1,3-Glucanase Genes in Nicotiana tabacum
| Autor: | Marc Cornelissen, Pierre Frendo, Dirk Inzé, M. Van Montagu, F. de Carvalho Niebel |
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| Přispěvatelé: | Universiteit Gent = Ghent University [Belgium] (UGENT) |
| Rok vydání: | 1995 |
| Předmět: |
0106 biological sciences
Nicotiana tabacum Transgene Genetically modified crops 01 natural sciences Homology (biology) [SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics 03 medical and health sciences Gene expression Gene silencing Gene 030304 developmental biology Regulation of gene expression 0303 health sciences Silence Case biology Gene Silence fungi food and beverages [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology Glucanase Activity [SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics biology.organism_classification Hemizygous Plant Molecular biology Cell biology Glucanase Gene 010606 plant biology & botany |
| Zdroj: | Current Topics in Microbiology and Immunology ISBN: 9783642791475 Gene Silencing in Higher Plants and Related Phenomena in Other Eukaryotes Gene Silencing in Higher Plants and Related Phenomena in Other Eukaryotes, 1995, 978-3-642-79147-5. ⟨10.1007/978-3-642-79145-1_7⟩ |
| DOI: | 10.1007/978-3-642-79145-1_7 |
| Popis: | International audience; Recent studies have demonstrated that introduction of sense gene constructs in plants can result in transgenic plants which express the transgene but also in plants with suppressed levels of transgene expression (reviewed by Jorgensen 1991; Kooter and Mol 1993; Matzke and Matzke 1993). In many silencing cases, the transgene and homologous host genes are coordinately suppressed in the plants, a phenomenon called co-suppression (Napoli et al. 1990). Although the underlying mechanism(s) are unknown, co-suppression has been reported in different plant species, and thus may represent a new approach to the manipulation of gene expression in plants. The finding that the presence of transgenes can influence the expression of resident genes via a homology-based mechanism opens up the possibility that this type of gene regulation may be naturally occurring in plants. A major challenge now is to unravel the molecular mechanism(s) responsible for transgene-induced gene silencing in plants. |
| Databáze: | OpenAIRE |
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