Posterior Reversible Encephalopathy Syndrome after Heart Transplantation: Diagnosis and Immunosuppressive Therapy
| Autor: | Aniruddh Kapoor, Andrew Lenneman, Kelly C. McCants, Emma J. Birks |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Graft Rejection medicine.medical_treatment Encephalopathy Case Reports 030204 cardiovascular system & hematology Tacrolimus 03 medical and health sciences 0302 clinical medicine medicine Humans Adverse effect Heart transplantation Sirolimus business.industry Drug Substitution Graft Survival Neurotoxicity Posterior reversible encephalopathy syndrome Immunosuppression medicine.disease Transplantation surgical procedures operative Diffusion Magnetic Resonance Imaging Treatment Outcome Anesthesia Heart Transplantation Female Posterior Leukoencephalopathy Syndrome Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Immunosuppressive Agents |
| Zdroj: | Texas Heart Institute journal. 44(3) |
| ISSN: | 1526-6702 |
| Popis: | Posterior reversible encephalopathy syndrome, an infrequent neurotoxicity associated with the use of tacrolimus, was first described in 1996, as a reversible syndrome manifested by headache, altered mental function, seizures, and visual disturbances. We describe the case of a 37-year-old woman who developed neurologic symptoms consistent with encephalopathy after treatment with tacrolimus, which was prescribed to maintain immunosuppression after orthotopic heart transplantation. This report also discusses the imaging methods used in the diagnosis of posterior reversible encephalopathy and highlights the difficulty of maintaining immunosuppression and managing medication-related adverse effects, while taking into account the risk of acute rejection after transplantation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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